BioM-7: BUGA-CoL Type-1 Collagen Lyophilized
TYPE-I COLLAGEN LYOPHILIZED FROM BOVINE TENDON.
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BUGA-CoL Lyophilized Type I Collagen from bovine tendon, It is produced in medical purity.
Collagen is the most important structural protein in the human body. Collagen fibers in bones, tendons, skin, articular cartilage, ligaments and muscles make up one third of our entire protein content. It provides the adhesion of the cells to the extracellular matrix surface with its adhesive feature. Collagen, especially with its high biocompatibility, biodegradability and low antigenicity, is considered as an ideal biomaterial for tissue scaffolding in tissue engineering and healthcare. BUGA-CoL, Lyophilized Type I Collagen from bovine tendon consists of approximately 97% Type I collagen and 3% of Type III collagen.
Fields of usage: It can be used in biomedical, microfluidic chip, tissue engineering, natural polymer for 3D printing, Material Science, Biochemistry and cell culture studies.
DATASHEET
| Specification | Info |
| Amount, Volume |
0.5, 1.0, 2.0, and 5.0, grams (Higher amounts are available upon request) |
| Material | Collagen from bovine tendon |
| Extraction Method | Enzymatic - Athelocollagen |
| Sterilization Method | Filtration |
| Appearance |
Physical state: Lyophilized Color: White |
| Solubility | 3 mg/mL (in 0.01 M HCl) |
| Dispersion | Complete dissolution at 0.01 M HCl |
| Odor | No data available |
| Storage Temperature |
Store lyophilized form at -20 ºC Store the solution at 2-10 ºC |
| Shelf Life |
Lyophilized form: At least 6 months from production date Solution form: At least 3 months from production date |
| pH | 1.8-2.1 |
| Purity- Silver staining | 98.9 |
| Electrophoretic Property - Commasie blue | Characteristic |
| Endotoxin / LAL | Lower than 10 EU/mL |
| ... | ... |
| Additional Requirements | Suggestions |
| Specified Use | It is intended for use only in research and development studies. |
| Microfluidic Tissue-on-Chips |
Suitable to be used in any microfluidic channel. Suggested to be used with tissu-on-chips |
| Not recommended use | Not suitable for consumption, medication, food and other uses |
These are some highly sited articles from literature. The chip designs are not identical but working is the same in principle.
| Erica Rosella et.al., 2020 |
| A microfluidic approach for development of hybrid collagen-chitosan extracellular matrix-like membranes for on-chip cell cultures |
| DOI:10.1016/j.jmst.2020.02.059 |
| G. Pagano et.al., 2014 |
| Optimizing design and fabrication of microfluidic devices for cell cultures: An effective approach to control cell microenvironment in three dimensions |
| DOI: 10.1063/1.4893913 |
| Brian Burkel et.al., 2016 |
| Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo |
| DOI: 10.3791/53989 |
| Keith B Neeves et.al., 2013 |
| Sources of Variability in Platelet Accumulation on Type 1 Fibrillar Collagen in Microfluidic Flow Assays |
| DOI: 10.1371/journal.pone.0054680 |
| Christian Haynl et.al., 2016 |
| Microfluidics-Produced Collagen Fibers Show Extraordinary Mechanical Properties |
| DOI: 10.1021/acs.nanolett.6b02828 |
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