SpS-Z50 Spiral Particle Sorting Chip

NBT Original

  • €49,00
    Unit price per 
Shipping calculated at checkout.


THIS IS A SPIRAL MICROFLUIDIC LAB ON A CHIP FOR PARTICLE AND CELL FOCUSING OR SEPARATION BY THEIR SIZES. IT IS SUITABLE TO SORT PARTICLES/CELLS LARGER THAN 3.5 MICRONS IN DIAMETER BY THE FORMULA OF [PARTICLE DIAMETER / Dh > 0.07] IN WHICH [Dh = 4 x SECTION AREA / PERIMETER].

SPS0 CONTAINS 4 DIFFERENT DEVICES OF 100um, 150um, 200um, and 300um MICROCHANNELS IN WIDTH.

OTHER SPS# MODELS ARE OF SAME 4 DEVICES WITH SAME WIDTHS OF 100um, 150um, 200um, and 300um.

ALL PRICES ARE WITHOUT VAT AND THE SHIPPING COSTS CAN BE SEEN AT THE SHOPPING CART AFTER PROVIDING SHIPPING ADDRESS.

 

 
...

--- Life Sciences: Circulating Tumor Cells (CTCs) detection and separation from raw blood,
--- Pharmaceutical Sciences:
--- Biotechnology: Cell filtration and separation/isolation after bioreactor synthesis
--- Diagnostic tech: Tumor cell identification
--- Others:

 


 DATASHEET
Specification Info
Number of devices per chip 4 devices
Material PDMS bonded on microscopy glass. Please also check the "Our Trip to PDMS Chips" blog post.
Bonding Technique Oxygen plasma treatment
XY Size of total chip 25x73 mm2 of the chip on 26x76 mm2 of std microscopy glass
Z Height of microchannels 50 micrometer
Z Height of PDMS chip 3.0 - 4.0 mm
Spiral number (all Devices) 4 spirals
The width of the channel (Device-#1) 100 um
The width of the channel (Device-#2) 150 um
The width of the channel (Device-#3) 200 um
The width of the channel (Device-#4) 300 um
Width between channels 500 um
The aspect ratio of spiral channels (width/height) 2/1 (Device#1), 3/1 (Device#2), 4/1 (Device#3), 6/1 (Device#4)
Ports on top/edge on Top
Number of ports 5 ports per device
Pitch btw ports and edge-to-port 3 mm and 3.5 mm
Size / Shape of ports 2 mm / Circle
Suitable Connector Outer Diameter 2.0 - 2.5 mm
microChannel geometry Rectangular
The layout of active ports  NA (Not Applicable)

 


 REQUIREMENTS

Additional Requirements Suggestions
Pumping/Actuation

The suggested initial flow rate is 1-3 mL/min
Inertial microfluidic sorting requires low-pulsation flow.
Some high-quality syringe pumps and pressure pumps work well.
Peristaltic, piezoelectric pumps are not suggested due to relatively high pulsation.

Fittings All fittings in ufluidic.com are suitable for this chip. Any other connectors compatible with pitch and port size are also applicable.
Chemicals No additional chemical is necessary
Visualization Epi-Fluorescent Microscopy is widely used together with chips to visualize separation of particles.
Since size separation occurs at high speed inside microchannels, recording may require high-fps cameras or photosensors regarding the application.

 


 LITERATURE

Application examples from literature

These are some highly sited articles from literature. The chip designs are not identical but working is the same in principle.

Ketpun D. et.al. 2017
The Viability of Single Cancer Cells after Exposure to Hydrodynamic Shear Stresses in a Spiral Microchannel: A Canine Cutaneous Mast Cell Tumor Model
DOI: 10.3390/mi9010009
Xiang N. et.al. 2015
Improved understanding of particle migration modes in spiral inertial microfluidic devices
DOI: 10.1039/c5ra13292d
Son J. et.al. 2015
Non-motile sperm cell separation using a spiral channel
DOI: 10.1039/c5ay02205c
Warkiani M.E. et.al. 2014
Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cells
DOI: 10.1039/C3LC50617G
Burke J.M. et.al. 2014
High-throughput particle separation and concentration using spiral inertial filtration
DOI: 10.1063/1.4870399
Kim T.H. et.al. 2014
Cascaded spiral microfluidic device for deterministic and high purity continuous separation of circulating tumor cells
DOI: 10.1063/1.4903501
Xiang N. et.al. 2013
Quantitative characterization of the focusing process and dynamic behavior of differently sized microparticles in a spiral microchannel
DOI: 10.1007/s10404-012-1025-4
Hou H.W. et.al. 2013
Isolation and retrieval of circulating tumor cells using centrifugal forces
DOI: 10.1038/srep01259
Nivedita N. and Papautsky I. 2013
Continuous separation of blood cells in spiral microfluidic devices
DOI: 10.1063/1.4819275
Sun J. et.al. 2012
Double spiral microchannel for label-free tumor cell separation and enrichment
DOI: 10.1039/c2lc40679a
Sun J. et.al. 2012
Hydrodynamic Cell Enrichment in Double Spiral Microfluidic Channels
DOI: 10.1149/05012.0441ecst
Nivedita N. et.al. 2012
Spiral Inertial Microfluidic Devices for Continuous Blood Cell Separation
DOI: 10.1117/12.909936
El-Hasni A. et.al. 2011
Focusing and Sorting of Particles in Spiral Microfluidic Channels
DOI: 10.1016/j.proeng.2011.12.295
Sathyakumar S. et.al. 2009
Inertial microfluidics for continuous particle separation in spiral microchannels
DOI: 10.1039/b908271a
 

 

 


Kullanım Kılavuzu  Yakında eklenecektir
Nasıl Kullanılır? - Multimedya  Yakında eklenecektir
Akış testi - Multimedya
Partikül Ayrım Testi - Multimedya  Yakında eklenecektir

 


We Also Recommend